Weight management can be a challenge for many of us. Weight gain itself is influenced by a range of factors including genetics, hormones, and socio-economic and environmental influences. It can also be a side of effect of some medications or health conditions, or as a result of unhealthy lifestyle habits such as poor diet and lack of exercise. Obesity is also a risk factor for many health conditions including high blood pressure, stroke, heart disease, type 2 diabetes, some cancers, respiratory issues, and bone and joint health. Maintaining a healthy weight and balanced lifestyle has a huge number of benefits for our overall health.
The role of GLP-1 and weight
Weight gain and obesity were initially thought to occur due to an imbalance between energy in (how much we eat) and energy out (how active we are). If we take in more calories than we burn through activity and exercise, we will put on weight. However, further research has shown that obesity is more complex that this, involving many body systems involved with hunger, satiety (how full we feel), and energy balance.
Research has shown that hormones released in the gut which help regulate blood glucose levels after eating play an important role in obesity. One of these hormones is glucagon-like peptide-1 otherwise known as GLP-1.
GLP-1 and its pharmacological equivalents lead to weight loss by acting on various body systems. These actions include:
- Suppressing appetite and food intake (so you feel less hungry and therefore eat less)
- Increasing satiety (the feeling of being full)
- Reducing gastric emptying of food (helping you feel fuller for longer)
- Improving fat metabolism by reducing white adipose tissue thickness
- Enhancing browning of adipose tissue (which helps to increase energy expenditure / burning of calories)
Blood Sugar Balance and GLP-1
Blood sugar balance is important when it comes to weight management because high levels of blood sugar can lead to increased appetite and fat storage.
GLP-1 is released in the intestine in response to eating and/or increased blood glucose levels. It helps support the action of insulin – a hormone which helps the cells in the body to take in glucose for energy - and reduces liver glucose production, which in healthy individuals results in lower blood glucose levels. Research therefore suggests that using natural botanicals which can mimic the effects of GLP-1 could help to maintain balanced blood sugar levels.
Eating a low GI (Glycaemic Index) diet which is rich in protein, fibre from wholegrains and vegetables, plus healthy fats can also help
to maintain blood sugar balance, alongside regular exercise and good quality sleep.
Short-Chain Fatty Acids (SCFAs) and fibre
There is growing evidence to suggest that the healthy bacteria in our gut has an impact on our metabolism by producing Short-Chain
Fatty Acids (SCFAs). SCFAs are a type of ‘metabolite’ which can influence our appetite and energy balance in the body.
Some dietary fibres including Glucomannan are fermented by our gut bacteria to produce SCFAs. The fermentation of glucomannan and the resulting SCFAs therefore can help to regulate our metabolism which in turn can help support a weight management programme.
How supplementation can help
When it comes to making changes to your lifestyle there will be some factors affecting weight management that you can take positive steps towards such as eating a well-balanced diet full of vegetables, wholegrain fibre, and good quality protein, being physically active, staying hydrated, and getting enough quality sleep.
Whatever may be impacting on your weight, there are vitamins, minerals, and botanicals which can help.
Botanicals:
There are a range of natural botanicals which may help support weight management
Green Tea helps to support weight control whilst Cinnamon helps to maintain a healthy blood glucose level as a part of a healthy lifestyle. Other botanicals include extracts of Fenugreek, Berberine, Olive leaf, Hibiscus, White Mulberry leaf, Blackcurrant, Maritime Pine Bark, Pomegranate, and Curcumin.
Dietary fibre:
Some fibres act as pre-biotics in the gut. The action of the gut bacteria on the fibre produces Short-Chain Fatty Acids (SCFAs) which in turn can help regulate metabolism.
Glucomannan contributes to the reduction in body weight in the context of an energy-restricted diet.
Vitamins and Minerals:
There are a number of essential nutrients that play an important role when it comes to weight management. Making sure we avoid micronutrient deficiencies is another way to help support our weight and overall health.
Vitamin B6 contributes to normal protein and glycogen metabolism whilst chromium contributes to the maintenance of normal blood glucose levels.

Here at Evera Nutrition, we realise that everyone’s experience of weight management is different. That’s why our team of scientists has created a unique formulation to support you on your journey, helping you to feel confident and in control.
