Our skin is a complex organ and works hard for us over our lifetime. It performs many important functions, protecting our bodies from pathogens, helping to regulate our temperature, and acting as a sensory organ to name but a few. It is no surprise that as we age, our skin starts to break down, becoming thinner and less elastic over time. The evidence of this is often most noticeable in our face and so finding ways to support our skin health from the inside out through diet, hydration, and supplementation can have a big impact on how our skin looks and how we feel about ourselves overall.
What causes skin ageing?
Skin ageing can reveal itself in a loss of elasticity and firmness, the appearance of fine lines and wrinkles, and in some cases hyperpigmentation in the form of age or sun spots.
This damage can be caused by a number of factors which fall into three broad categories:
Internal
- Time - just getting older
- Physiological changes such as the menopause
- As a side effect of some medications
Environmental
- Ultraviolet (UV) radiation – for example, exposure to the sun’s rays
- Air Pollution – for example, car exhaust fumes, dust and soot, industrial processes
- Wind exposure (which can strip skin of its
natural oils and reduce moisture levels)
Lifestyle
- Tobacco smoking
- Excessive alcohol intake
- Poor dietary habits
- Dehydration
- Increased stress levels
- Lack of sleep or poor-quality sleep
Theories on Skin Ageing:
We know what causes skin ageing but what actually happens in the body as a result of these internal, environmental, and lifestyle factors is the subject of much research.
There are four core theories as to what is taking place:
Free radicals and oxidative stress theory
Free radicals - molecules that can cause damage in our bodies - are one of the main causes of skin ageing. If there is an imbalance between free radicals and our body’s ability to get rid of them, this can lead to oxidative stress which can detrimentally affect the functioning of cells within the body. It is this damage which can accelerate ageing and cause a decrease in the collagen levels in skin tissue, leading to skin relaxation and wrinkles.
Limiting exposure to free radicals whether through environmental factors or taking steps to improve associated lifestyle factors is an important strategy for preventing skin ageing.
Inflammation theory and senescent cells
Senescent cells are cells in the body which have permanently stopped dividing but haven't died. They are sometimes referred to as "zombie cells" because they stay in the body but without dividing or dying. These cells release substances which can cause inflammation and damage to healthy cells which can lead to the ageing of body cells, including the skin, and is also associated with a range of ageing diseases.
Inflammation itself is also one of the major causes of senescent cells. Inflammation can cause fibroblasts (cells which contribute to connective tissue and secrete collagen proteins) and keratinocytes (cells that form the outer layer of the skin) to become senescent and stop doing their jobs. These senescent cells then release substances which cause more inflammation and damage which leads to more senescent cells, and so the cycle continues.
Preventing skin cell inflammation is one of the most important strategies to help control skin cell ageing.
Photoageing theory
Ultraviolet (UV) light such as that emitted by the sun can lead to skin ageing. Long term exposure to solar UV radiation will cause photoaging, which will affect skin pigmentation, immunity, and the vascular system. Adult dermal collagen content decreases every year. This decrease can lead to visible changes to the skin structure including wrinkles and a loss of elasticity.
Exposure to UV radiation stimulates keratinocytes and fibroblasts to release substances which degrade important skin components such as collagen.
Limiting exposure to UV radiation is another important strategy to prevent skin cell ageing.
Glycosylation theory
According to this theory, something called ‘glycosylation’ causes damage to proteins which in turn leads to ageing. Glycosylation is a reaction in the body between sugars, proteins, DNA, and lipids (fats). This process produces Advanced Glycation End-products (AGEs). The accumulation of AGEs affects skin cells and causes protein structure changes, leading to skin darkening and skin ageing. The accumulation of AGEs also leads to inflammation, which as we have seen above in ‘Inflammation Theory’ further accelerates skin ageing. The higher the levels of glycosylation, the more rapidly skin cells will age.
The formation of AGEs is irreversible, so inhibiting skin glycosylation is also one of the important ways to control skin ageing.
Ways to prevent skin ageing
Reducing the accumulation of AGEs and senescent cells
AGEs can be combatted with ingredients with proven capabilities to address these issues.
Reaching deeper skin layers
Whilst topical products in our skincare routines primarily affect the outer layers of the skin, intake of essential nutrients through our diet, alongside good levels of hydration and targeted supplements can reach deeper layers, improving skin structure, elasticity, and hydration from within.
Targeting specific skin concerns
Certain supplements, like collagen peptides, hyaluronic acid, and antioxidants, can be used to target specific ageing concerns, such as wrinkles, loss of elasticity, and uneven skin tone.
Boosting antioxidant defence
Oxidative stress from sun exposure and other factors contributes to skin ageing. Supplements such as vitamin C, vitamin E, and other antioxidants can help combat free radicals and protect against skin damage.
Enhancing collagen production
Collagen is a key protein for skin structure. Collagen peptides, hyaluronic acid, and other nutrients support collagen synthesis, and can improve skin firmness and reduce the appearance of wrinkles.
Improving skin hydration
Alongside increasing your intake of water and staying well hydrated, supplements can help retain moisture in the skin, contributing to a plumper, more hydrated appearance.
Supporting overall skin health
Certain vitamins, minerals, and botanicals play a role in overall skin health by supporting barrier function, reducing inflammation, and promoting cell regeneration.
How supplementation can help
When it comes to making changes to your lifestyle there will be some factors affecting skin ageing that you can take positive steps towards such as eating a well-balanced diet full of antioxidants from colourful fruits and vegetables alongside good quality protein, staying hydrated, getting enough quality sleep, and minimising sun exposure.
Whatever may be impacting on your skin, there are vitamins, minerals, and botanicals which can help.
Collagen support:
Collagen is the most abundant protein in the body and forms the basis of hair, skin and nails, as well as bones, tendons and cartilage.
Collagen supplementation is a good way to support levels of collagen in the body whilst vitamin C contributes to normal collagen formation.
Antiglycaction (preventing AGEs):
Research suggests that certain nutrients and botanicals can help to improve different areas which can affect our skin health such as hydration, elasticity, and trans epidermal water loss which all contribute to healthier and younger-looking skin.
Grapeseed extract helps to promote healthy, radiant skin. Other nutrients include all eight B vitamins, vitamin C, selenium, manganese, Co Enzyme Q10, astaxanthin, carnitine, resveratrol, and specific extracts of Maritime Pine Bark, Milk Thistle, Ecklonia kava, Green Tea, Curcumin, and Chamomile.
Hydration:
Hyaluronic acid is a naturally occurring substance which attracts and retains moisture.
Ensuring skin is well hydrated can help to support firmer, more plump-looking skin. Well-hydrated skin can help reduce the appearance offine lines and wrinkles and make skin appear smoother.
Vitamins and Minerals:
There are a number of essential nutrients that play an important role when it comes to our hair, skin, and nails. Making sure we avoid micronutrient deficiencies is another way to help support our outward appearance.
Biotin contributes to normal hair and skin whilst vitamin A also helps to support normal skin. Zinc contributes to normal hair, skin, and nails whilst vitamin E helps protect cells from oxidative stress.

Here at Evera Nutrition, we realise that everyone’s skin is different. That’s why our team of scientists has created a unique formulation to support your skin health, helping you to look your radiant best at any age.
